Periodicidad semestral: flujo continuo.
ISSN - Electrónico: 2661-6947 / DOI: 10.36015 • LILACS BIREME (19784); LATINDEX (20666)
INTRODUCTION: Mechanical ventilation release protocols do not consider cardiac performance during a very challenging test such as the spontaneous ventilation test.
OBJECTIVES: To determine whether the variation of central venous oxygen saturation and venous
serum lactate can predict failure of mechanical ventilation release in patients who overcame septic shock at the Carlos Andrade Marín Hospital during the period October 2018 to June 2019.
MATERIALS AND METHODS:
A descriptive, observational, cross-sectional study was developed. The data was analyzed of 62 patients were obtained during this period, with a 69.6% higher
prevalence of the male gender. The median age is 62 years (IQR 47-80) where 46.8% belong to the group over 65 years. The average number of hospitalization days is 9.8 ± 5.94 days. The average of mechanical ventilation days was 5.54 with a standard deviation of 3.2 days. The APACHE II average
at admission was 20.41 ± 6.50. The infection site with the highest prevalence was pulmonary with a
representativeness of 50%. The average value for the SOFA at the time of the test was 6.19 ± 2.98.
The 75.8% of patients showed success in mechanical release. The reintubation rate was 11.29%.
The cut-off point for the central venous saturation delta was greater than 4.5% with a sensitivity of
91, 43% and a specificity of 66.6%, (OR = 12.28; 95% CI 2.90: 51,94), VPP; 53.3% and NPV; 86%
ROC; 84.10% (95% CI 71.6%; 96.6%). Serum venous lactate was not significant to predict mechanical release failure. The significant covariates for the regression model are APACHE II at admission and
the Charlson Index with a 90.3% prognosis of failure in ventilation release and a significance for the
model of p = 0.00.
CONCLUSIONS: The difference in central venous oxigen saturation was significat to predict the failure in the release of mechanical ventilation.
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