Periodicidad semestral: flujo continuo.
ISSN - Electrónico: 2661-6947 / DOI: 10.36015 • LILACS BIREME (19784); LATINDEX (20666)
Introduction: Gliomas are among the most common primary brain malignant tumors. They are relatively infrequent lesions compared with others neoplasms, though, they are associated with both, high mortality and morbidity. The main objective was to define the rate of mortality and describe clinical manifestation in patients with glioma newly diagnosed. Methods: We conducted a retrospective review that assessed clinical manifestations, treatment and mortality at Carlos Andrade Marín hospital, Quito Ecuador, over a period going from January 2012 to December 2013. The study design was a case series. Results: We reported 42 patients with glioma newly diagnosed. Mean (SD) age was 50(±16.6) year-old. The most common symptoms reported on admission were headache, seizures and headache and hemiparesia. According to the WHO classification, we had one (2%) patient grade I , 25 (60%) patients grade II, 12 (29%) patients grade III and four (10%) grado IV. Overall mortality rate at two yearse was 57%. Patients older than 40 y.o had worse prognosis (p=0.0002). Discusion: Clinical features do not differ from other published studies and the mortality was higher in patients with low-grade glioma with poor Karnofsky Performance Status Scale.
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