Periodicidad semestral: flujo continuo.
ISSN - Electrónico: 2661-6947 / DOI: 10.36015 • LILACS BIREME (19784); LATINDEX (20666)
INTRODUCTION. Diabetic Nephropathy is a chronic vascular complication that causes
a series of functional and structural alterations, mainly at the glomerular level. Cystatin C
and serum creatinine are markers of kidney function. OBJECTIVE. To correlate the tests of
renal function cystatin C and serum creatinine against glomerular filtration in patients with
Diabetic Nephropathy. MATERIALS AND METHODS. Descriptive, cross-sectional study. From a population of 418, a sample of 124 data from Medical Records was selected. The data from the measurement results of cystatin C and serum creatinine were analyzed against glomerular filtration of patients with Diabetic Nephropathy in the period from june to december 2017. RESULTS. Frequency of age from 36 to 93 years, means: 69 years, standard deviation 10,76; 56% (69; 124) of the female sex and 44% (54; 124) of the male sex. Cystatin C vs serum creatinine versus glomerular filtration showed a correlation of 92% (114; 124) and 66% (81; 124), respectively, was obtained, a higher correlation was obtained with cystatin C and a close bilateral significance of 0,000. The most frequent kidney damage was stage II in patients aged 66 to 75 years. CONCLUSION. Cystatin C and serum creatinine showed a high correlation with glomerular filtration in patients with Diabetic Nephropathy, the main one being cystatin C, which detected early changes in the filtrate.
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