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Revista Médica Científica CAMbios

Periodicidad semestral: flujo continuo.

ISSN - Electrónico: 2661-6947 / DOI: 10.36015 • LILACS BIREME (19784); LATINDEX (20666)

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Keywords

Sepsis
Critical Care
Prognosis
Shock septic
Intensive Care Units
Organ Dysfunction Scores

How to Cite

1.
Validation of SOFA score in sepsis patients in the Intensive Therapy Unit of Teodoro Maldonado Carbo Hospital 2016 - 2017. Cambios rev. méd. [Internet]. 2019 Jun. 29 [cited 2025 Dec. 7];16(2):21-4. Available from: https://revistahcam.iess.gob.ec/index.php/cambios/article/view/351

Abstract

Introduction: Sepsis is a public health issue. Worldwide, it is estimated that 31.5 million new cases occur annually, which means an increase in the cost of health systems and a high mortality of these patients in the Intensive Care Units-ICU. There are some scales and methods to describe the severity of the disease that can predict the result of medical care for patients in critical condition like the Sequential Organ Failure Assessment  (SOFA)  Score.  Several  studies  indicate and  support  its  use  as  a  predictor  of  death  within 30 days. The objective of this study to assess the performance of the SOFA score in a teaching hospital, in three instances: at admission to the ICU, and after 48 and 96 hours, in order to predict mortality in critical care  patients  with  the diagnosis  of septicemia  in a teaching hospital. Methods: Cases series with ICU patients at a tertiary hospital   from   Guayaquil   city.   SOFA   score   was assessed and ROC curves obtained. Results: The study included 100 patients, the median age of the group was 65.3 years; the death rate was 56% and the median hospital stay was 21.2 days. In the COR-SOFA curve, the death rate corresponds to the area below the SOFA curve. On admission,  the SOFA score was: 0.62, then after 48 and 96 hours, the SOFA score was 0.74 and 0.79, respectively. The positive predictive value was 81.8% [IC 95 %: 68.0 - 90.5]. Discussion: The SOFA score is a predictive tool for mortality in sepsis that has been validated in several studies, however, in our case series we determined that sensitivity and specificity was not conclusive. We find that SOFA score at 96 hours has a better sensitivity and specificity than earlier measurements.

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