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Revista Médica Científica CAMbios

Periodicidad semestral: flujo continuo.

ISSN - Electrónico: 2661-6947 / DOI: 10.36015 • LILACS BIREME (19784); LATINDEX (20666)

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Keywords

Scleroderma, Systemic
Liver Cirrhosis, Biliary
Rheumatology
Pathology
Biopsy
Cholangitis

How to Cite

1.
Reynolds Syndrome in Carlos Andrade Marin Hospital: a series of cases and review. Cambios rev. méd. [Internet]. 2016 Jul. 31 [cited 2025 Jun. 1];15(2):47-50. Available from: https://revistahcam.iess.gob.ec/index.php/cambios/article/view/319

Abstract

Introduction: The Reynolds’ syndrome is the combination of systemic sclerosis (SSC) and primary biliary cirrhosis (PBC). It was first described in 1934 by Milbradt. Reynolds in 1976 presented six cases in two of them and fibromax-test in another. Case report: We present three cases of three women treated in the Rheumatology department at Carlos Andrade Marin hosppital who had autoinmune liver disease confirmed by biopsy. Discusion: Recognizing Reynolds’ Syndrome allow us to make earlier diagnosis. This autoimmune cholestatic liver disease often remains silent, so that their identification is a valuable diagnostic tool leading to therapeutic interventions.

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References

Rigamonti C et al. Review Article. Primary Biliary Cirrhosis Associated with Systemic Sclerosis: Diagnostic and Clinical Challenges. Hindawi Publishing Corporation International Journal of Rheumatology. Volume 2011, Article ID 97627, 12 pages doi: 10.1155/2011/976427

Cabral L et al. Síndrome de Reynolds. CREST asociado a cirrosis biliar primaria. Dermatol Argent 2008; 14(4): 276-280.

Sanchez A et al. Cirrosis biliar primaria: Aspectos clínico epidemiológicos en una población uruguaya. Acta Gastroenterol Latinoam 2013; 43(4): 288-293

Rebollo N, Vega E, Arenas R. Síndrome de Reynolds: Un caso con cirrosis biliar primaria y esclerodermia. Dermatología CMQ 2007; 5(3):155-157

Mayo M et al. " Association of clonally expanded T cells with the syndrome if primary bilary cirrhosis and limited scleroderma,” Hepatology 1999, 29(6): 1635–1642.

Bernstein R et al. Anticentromere antibody in primary biliary cirrhosis. Ann Rheum Dis 1982; 41: 612-614

Dahnrich C et al. New ELISA for Detecting Primary Biliary Cirrhosis - Specific Antimitochondrial Antibodies. Clinical Chemistry 2009; 55(5): 978–985

Corpechot C et al. Assessment of Biliary Fibrosis by Transient Elastography in Patients With PBC and PSC. HEPATOLOGY 2006; 43: 1118-1124

Fonollosa V et al. “Morphologic capillary FKDQJHV DQG PDQLIHVWDWLRQV RI FRQQHFWLYH tissue diseases in patients with primary biliary cirrhosis,” Lupus 2001; 10(9): 628–631.

Rigamonti C. Clinical features and prognosis of primary biliary cirrhosis associated with systemic sclerosis. Gut 2006; 55: 388–394.

Tyndal A et al. Causes and risk factors for death in sistemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database. Annals of the Rheumatic Diseases 2010; 69 (10): 1809-1815

European Association for the Study of the liver. EASL Clinical Practice Guidelines: Management of cholestatic liver diseases. Jpurnal of Hepatology 2009; 51: 237–267

Paumgartner G. Ursodeoxycholic acid for primary biliary cirrhosis: treat early to slow progression. Journal of Hepatology 2003; 39:112–114

 

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