Periodicidad semestral: flujo continuo.
ISSN - Electrónico: 2661-6947 / DOI: 10.36015 • LILACS BIREME (19784); LATINDEX (20666)
Persistent Pulmonary Hypertension of the Newborn (PPHN) in a medical emergency in the neonatal stage with high morbidity and mortality in neonates.
This is characterized by a sustained elevation in pulmonary vascular resistance (PVR). Previously referred to as persistent fetal circulation which is usually the result of incomplete lung transition at birth. The cause may be idiopathic, a consequence of prenatal drug therapy management, pneumonia, sepsis, or a congenital diaphragmatic hernia with pulmonary hypoplasia. Described for the first time by Gerson et al. in 1969, this pathology occurs in 2 to 6 out of every 1 000 live newborns and it is estimated that 7 to 20% of newborns who survive PNPH develop alterations in the medium or long term such as chronic lung disease, hearing impairment, intracranial hemorrhage and neurological sequelae1. Mortality reported in the literature varies between 10 and 20% and between 10 and 50% in developing countries. The mortality rate has decreased a lot in the last decade, but much remains to be done to improve neonatal care for this condition in many areas of countries in the Latin American region2.
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