
Periodicidad semestral: flujo continuo.
ISSN - Electrónico: 2661-6947 / DOI: 10.36015 • LILACS BIREME (19784); LATINDEX (20666)
INTRODUCTION. Pyogenic liver abscesses in neonates are a rare entity with less than one hundred cases reported in the world literature. Diagnosis at this age is difficult because both signs and symptoms are nonspecific and are related to sepsis. OBJECTIVES. Identify the clinical and pathological characteristics of liver abscess in neonates and correlate to the positioning of umbilical catheters in the liver as an associated risk factor for developing liver abscess in neonates. MATERIALS AND METHODS. Retrospective, descriptive study, case reports, with a sample and known population, of 5 newborn patients. Inclusion Criteria: neonates of both sexes with gestational age over 34 weeks of gestation, with a history of poor positioning of umbilical catheters documented by an “x-ray” imaging exam. Exclusion Criteria: patients without a history of umbilical catheterization and / or who have not been documented by imaging study with evidence of the catheter incorrectly placed in liver tissue. The database registered in the archives of the Pediatric Gastroenterology Service of the requested interconsultations of the Neonatal and Neonatal Intensive Care Unit of the Civil Hospital of Guadalajara “Dr. Juan I. Menchaca ”. Jalisco- Mexico, in a time of 5 years, from January 2013 to 2018. RESULTS. There were five pre terms (n = 5) between 34 and 36 weeks, with an average gestational age of 35 weeks and 2039 grams of birth weight. The average number of days for diagnosis was 7,8. Four patients had 80,0% hepatomegaly (4; 5), the volume of abscesses was between 2 and 12mm in the right hepatic lobe. CONCLUSION. Hepatic abscess is uncommon but its clinic should be suspected in a newborn with sepsis and a history of umbilical catheterization. Management and favorable clinical evolution in 100,0% (5; 5) of infants and no surgical resolution was required.
Foster JH. History of liver surgery. Arco Surg[Internet]. 1991 Mar[cited 2019 Jan 01];126(3):381-7. Doi:10.1001/archsurg.1991.01410270131020. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/1998481
Tam N, Sriram B, Tan-Kendrick, Rajadurai VS. Neonatal Hepatical Abscess in preterm infants: A rare entity?, Annals Academy of Medicine[Internet]. 2005 Oct 01[cited 2019 Jan 01]; 34(9): 558-564. PMID:16284678. Available from: https://europepmc.org/abstract/med/16284678
Moss TJ, Pysher TJ. Hepatic abscess in neonates. Am J Dis Child[Internet]. 1981 Aug[cited 2019 Jun 01];135(8):726-8. Disponible en PMID: 7270515. Available from: https://www.ncbi.nlm.nih.gov/pubmed/7270515
Guillois B, Guillemin MG, Thoma M, Sizun J, Monnery JL, Alix D. Neonatal pleuropulmonary staphylococcal infection with multiple abscesses of the liver. Ann Pediatr (Paris)[Internet].1989 Dec[cited 2019 Jan 01];36(10):681-4. PMID: 2696413. Available from: https://www.ncbi.nlm.nih.gov/pubmed/2696413
Semerci SY, Babayigit A, Cebeci B, Buyukkale G, Cetinkaya M. Hepatic abscesses in preterm infants: Report of three cases and review of the literature. J Trop Pediatr[Internet]. 2016 Jan 11[cited 2019 Jan 01];62(3):255-60. DOI: 10.1093/tropej/fmv103. Available from: https://academic.oup.com/tropej/article/62/3/255/2363027
Habsaha H, Zeehaidaa H, Rostenbergheb V, Noraidab WI, Pauzib I, Fatimahb AR, et al. An outbreak of Pantoea spp. in a neonatal intensive care unit secondary to contaminated parenteral nutrition. Journal of Hospital Infection[Internet]. 2005 April 20[cited 2019 Jan 01];61(3):213–218. DOI:10.1016/j.jhin.2005.01.004. Available from: https://www.journalofhospitalinfection.com/article/S0195-6701(05)00047-2/abstract
Carvajal GA, Corrales IF, Cuenca MC, Troncoso GA. Absceso hepático secundario a cateterización umbilical en un recién nacido. Infectar [Internet]. Diciembre 2014 [citado 2019 Jan 01]; 18(4):158-161. DÓI:http://dx.doi.org/10.1016/j.infect.2014.04.0020123-9392. Disponible en: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S012393922014000400006&lng=en.
Simeunovic E, Arnold M, Sidler D, Moore SW. Liver abscess in neonates. Pediatr Surg Int[Internet].2009 Feb [cited 2019 Jan 01]; 25(2):153–156. DOI 10.1007/s00383-008-23075. Available from: https://link.springer.com/article/10.1007/s00383-008-2307-5
M’hamdi K, Kabiri M, Karboubi L, Ghanimi Z, Barkat A. Neonatal liver abscess after umbilical venous catheter. Arco Pediatric[Internet]. 2013 Feb;20(2):196-198 . DOI: 10.1016/j.arcped.2012.11.012. Available from: https://www.ncbi.nlm.nih.gov/pubmed/23305752
Sharma D, Choudhary M, Shastri S, Sharma PK. Neonatal liver abscesses due to Candida infection in a preterm infant, secondary to malpositioned umbilical lines – a rare entity. Pathogens and Global Health[Internet]. 2015[cited 2019 Jun 01];109(2):84-87. DOI: 10.1179/2047773215Y.0000000008. Available from: https://www.ncbi.nlm.nih.gov/pubmed/25736870
Cascio A, Pantaleo D, Corona G, Barberi G, Delfino D, Romeo O. Neonatal liver abscesses associated with candidemia: three cases and review of literatura. J Matern Fetal Neonatal Med[Internet]. 2013 Aug 27[cited 2019 Jun 10];27(7):743–749. DOI: 10.3109/14767058.2013.837878. Available from: https://www.infectoforum.net/neonatal-liver-abscesses-associated-with-candidemia-three-cases-and-review-of-literature/
Gálvez EA, Peralta JJ, Lonngi G. Sepsis temprana en un recién nacido pretérmino por Pantoea agglomerans: informe de caso y revisión de la literatura. Acta Pediatr Mex[Internet]. 2018 Feb[cited 2019 Jun 10];39(1):52-59. DOI: http://dx.doi.org/10.18233/apm1no1pp52-591540. Disponible en: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0186-23912018000100052&lng=es&nrm=iso
Bosnalı O, Moralıoğlu S, Cerrah A, Pekta O. Liver Abscess: Increasing Occurrence in Premature Newborns. Cirugía neonatal J[Internet] 2013 Apri- Jun[cited 2019 Jun 10];2(2):23. PMCID: PMC4420374. PMID: 26023443. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420374/
Carballo C, Cazes C, Matsuda M, Praino L, Rivas N, López E. Absceso hepático piógeno en pediatría: experiencia en un centro pediátrico de referencia. Rev Chilena Infectol[Internet]. 2017 Ene 17[cited 2019 Jun 10]; 34 (2): 128-132 Disponible en: https://scielo.conicyt.cl/pdf/rci/v34n2/art05.pdf
Fusaro F, Lo Piccolo R, Scarpa MG, Orzali A, Trafojer U, Zanon GF. Hepatic abscess and umbilical venous catheter: one cannot be cavalier about proper position. J Vasc Access[Internet]. 2003 Jan-Mar[cited 2019 Jan 10];4(1):32-4. DOI: 10.5301/JVA.2008.4791. Available from: https://www.ncbi.nlm.nih.gov/pubmed/24122331
Barakat N, Sirnivasagam R, Abdou E. Liver Abscess in Preterm Newborns Following Umbilical Venous Catheters. Med. J. Cairo Univ[Internet]. 2009 Sep[cited 2019 Feb 10]; 77(2): 189-192. Available from: https://pdfs.semanticscholar.org/beaf/856d1f7d8746a4e2a705038c5d1eb21130dc.pdf
Halvorsen RA, Korobkin M, Foster WL, Thompon WM. The variable CT appearance of hepatic abscesses. American Journal of Roentgenology[Internet]. 1984 May[cited 2019 Feb 10];142(5) 941-946. 1984;142(1):941-6. DOI:10.2214/ajr.142.5.941. Available from: https://www.ajronline.org/doi/abs/10.2214/ajr.142.5.941
Halvorsen RA, Korobkin M, Foster WL, Thompon WM. The variable CT appearance of hepatic abscesses. American Journal of Roentgenology[Internet]. 1984 May[cited 2019 Feb 10];142(5) 941-946. 1984;142(1):941-6. DOI:10.2214/ajr.142.5.941. Available from: https://www.ajronline.org/doi/abs/10.2214/ajr.142.5.941
Taguchi T, Ikeda K, Yakabe S, Kimura S. Percutaneous drainage for post-traumatic hepatic abscess in children under ultrasound imaging. Pediatr Radiol[Internet]. 1988[cited 2019 Feb 11];18(1)85-7. PMID: 3277146. Available from: https://www.ncbi.nlm.nih.gov/pubmed/3277146
Singh A, Gupta A, Ansari M. Neonatal Liver Abscess with Impending Rupture Presenting as Abdominal Wall Swelling: A Rare Case. Journal of Clinical Neonatology[Internet].2017[cited 2019 Mar 11];6(4):270-272. DOI: 10.4103/jcn.JCN_55_17. Available from: http://www.jcnonweb.com/article.asp?issn=22494847;year=2017;volume=6;issue=4;spage=270;epage=272;aulast=Singh
Gerzof SG, Johnson WC, Robbins AH, Naseth DC. Intrahepatic pyogenic abscesses: treatment by percutaneous drainage. Am J Surg 1985 Apr;149(4):487-494. Disponible en PMID: 3885778. DOI:https://doi.org/10.1016/S0002-9610(85)80045-3 Available from: https://www.ncbi.nlm.nih.gov/m/pubmed/3885778/
Gerzof SG, Johnson WC, Robbins AH, Naseth DC. Intrahepatic pyogenic abscesses: treatment by percutaneous drainage. Am J Surg 1985 Apr;149(4):487-494. Disponible en PMID: 3885778. DOI:https://doi.org/10.1016/S0002-9610(85)80045-3 Available from: https://www.ncbi.nlm.nih.gov/m/pubmed/3885778/
Barakate MS, Stephen MS, Waugh RC, Nabseth DC, Gallagher PJ, Solomon MJ, et at. Pyogenic liver abscess: a review of 10 years’ experience in management. Aust N Z J Surg[Internet].1999 April[cited 2019 Mar 11];69(2):205-9. Disponible en PMID:10075360. Available from: https://www.ncbi.nlm.nih.gov/pubmed/10075360
Sauto S, Ferrari I, Berazategui R, and cols. Abscesos hepáticos múltiples en pediatría: presentación de un caso clínico. Arch Pediatr Urug[Internet].2002 [cited 2019 Apr 19]; 73(3):140-142. ISSN 1688-1249. Available from: http://www.scielo.edu.uy/scielo.php?script=sci_serial&pid=1688-1249&lng=en
The authors who publish in this journal accept the following conditions:
1. The authors retain the copyright and grant to the CAMbios MEDICAL-SCIENTIFIC JOURNAL HECAM the right of the first publication, with the work registered with the Creative Commons attribution license, which allows third parties to use the published material provided that they mention the authorship of the work and the first publication in this journal.
2. Authors can make other independent and additional contractual agreements for the non-exclusive distribution of the version of the article published in this journal (for example, include it in an institutional repository or publish it in a book) as long as it clearly indicates that the work was published. for the first time in the CAMbios MEDICAL-SCIENTIFIC JOURNAL HECAM.