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Revista Médica Científica CAMbios

Periodicidad semestral: flujo continuo.

ISSN - Electrónico: 2661-6947 / DOI: 10.36015 • LILACS BIREME (19784); LATINDEX (20666)

Revista Médica Científica CAMbios Vol. 19(1) Ene-Jun 2020
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Keywords

HLA-B27 Antigen
Quality of Life
Spondylitis Ankylosing
Rheumatology
Biological Treatment
Uveitis

How to Cite

1.
Evaluate quality of life and the function in patients with ankylosing spondylitis. Cambios rev. méd. [Internet]. 2020 Sep. 30 [cited 2025 Nov. 23];19(1):62-8. Available from: https://revistahcam.iess.gob.ec/index.php/cambios/article/view/475

Abstract

INTRODUCTION. Ankylosing Spondylitis compromises the quality of life of the patient as it is a disease of axial, ocular, gastrointestinal and articular disabling affectation that limits basic activities of daily life that affects the social environment. OBJECTIVE. To evaluate the quality of life, functionality and activity of the disease in patients with Ankylosing Spondylitis. MATERIALS AND METHODS. Analytical transversal study, with a population of 166 patients, a sample of 120 with a diagnosis of Ankylosing Spondylitis from the “Unidad Técnica de Reumatología del Hospital de Especialidades Carlos Andrade Marín”. A structured questionnaire was applied to measure physical activity, presence of Human Leukocyte Antigen B-27, using internationally validated scales that evaluated quality of life, functionality and disease activity. Univariate, bivariate and multivariate analysis was calculated with Chi-square and Odds Ratios in the statistical program SPSS 23.0. RESULTS. A 50% (60; 120) of slight affectation in quality of life was observed, in functionality 74,2% (89; 120) presented affectation while in disease activity the Ankylosing Spondylitis Disease Activity Score found high activity with 43,3% (52; 120) and in Bath Ankylosing Spondylitis Disease Activity Index 55% (66; 120) of active disease. Combined treatment presented a greater risk of affecting functionality, low, high and very high disease activity with p values of 0,022; 0,014 and 0,026, respectively. CONCLUSION. Quality of life was affected in women and those who did not carry out physical activity; functionality was found to be compromised in those who received combined treatment.

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