Periodicidad semestral: flujo continuo.
ISSN - Electrónico: 2661-6947 / DOI: 10.36015 • LILACS BIREME (19784); LATINDEX (20666)
Introduction: tuberculous meningitis is one of the most common public health problems worldwide. Thwaites diagnostic scale is a tool used to differentiate tuberculous meningitis from other types of bacterial meningitis. Methods: This is a retrospective study carried out in patients diagnosed of bacterial meningitis developed at Carlos Andrade Marin Hospital. Information was taken from the medical records stored in the AS400 system. Results: Of 48 patients studied, 41 had bacterial meningitis and seven tuberculous meningitis. The sensitivity and the specificity of Thwaites’ diagnostic score were 88%. The LR+ and LR- were 7.33 y 0.14 respectively. Discusion: Thwaites’ diagnostic score was found to be a useful tool to differentiate bacterial from tuberculous meningitis.
World Health Organization. Global tuberculosis report 2014. acceso el 20 abril del 2016. Disponible en: http://apps.who.int/iris/ bitstream/10665/137094/1/9789241564809_eng.pdf?ua=1
World Health Organization. Global tuberculosis report 2014. acceso el 20 abril del 2016. Disponible en: http://www.who.int/tb/country/data/profiles/es/
Thwaites, G.E., Martin, F., Hemingway,C., Scott, g., Solomon, T., Innes, J. British Infection Society guidelines for the diagnosis and treatment of tuberculosis of the central nervous system in adults and children. J Infect. 2009; 59:167-187
Kurien R, Sudarsanam TD; Samantha S, Thomas K. Tuberculous meningitis: a comparison of scoring systems for diagnosis. Oman Med J. 2013 May; 28(3):163-6. doi: 10.5001/
omj.2013.47.
Thwaites GE, Chau TT, Stepniewska K, Phu NH, Chuong LV, Sinh DX, White NJ, Parry CM, Farrar JJ. Diagnosis of adult tuberculous meningitis by use of clinical and laboratory features. Lancet. 2002 Oct 26; 360(9342):1287-92.
M. Ramírez-Lapausa, A. Menéndez-Saldaña y A. Noguerado-Asensio Tuberculosis extrapulmonar, una revisión. Rev. esp. sanid. penit. vol.17 no.1 Barcelona. 2015
Martín Lasso B. Meningitis tuberculosa: claves para su diagnóstico y propuestas terapéuticas. Rev Chil Infect 2011; 28(3): 238-247
Sunbul M, Atilla A, Esen S, Eroglu C, Leblebicioglu H. Thwaites’ diagnostic scoring and the prediction of tuberculous meningitis. Med Princ Pract. 2005; 14:151-4.
Cruzate HH. Valoración del score de Thwaites para el diagnóstico de miningitis tuberculosa en pacientes hospitalizados en el servicio de medicina interna con el diagnóstico de meningitis en los años 2003-2012 del Hospital Nacional Hipólito Unanue [Tesis]. Lima: Universidad Nacional Mayor de San Marcos. Facultad de Medicina Humana.Escuela de Post- Grado; 2014.
Zhang YL, Lin S, Shao LY, Zhang WH, Weng XH. Validation of thwaites ‘diagnostic scoring system for the differential diagnosis of tuberculous meningitis and bacterial meningitis. Jpn J Infect Dis. 2014; 67(6):428-31
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