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Revista Médica Científica CAMbios

Periodicidad semestral: flujo continuo.

ISSN - Electrónico: 2661-6947 / DOI: 10.36015 • LILACS BIREME (19784); LATINDEX (20666)

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Keywords

Appendicitis/complications
Anti-Bacterial Agents
Metronidazole
Ampicillin
Cephalexin
Gentamicins

How to Cite

1.
Comparison of antibiotic therapy in complicated appendicitis in pediatrics. Cambios rev. méd. [Internet]. 2021 Sep. 29 [cited 2025 Nov. 23];20(1):21-5. Available from: https://revistahcam.iess.gob.ec/index.php/cambios/article/view/585

Abstract

INTRODUCTION. Acute appendicitis is a pediatric surgical pathology that in its complicated phase requires the use of antibiotics during the postoperative period; finding the best option as local experience was a must. OBJECTIVE. Compare a triple vs a double antibiotic therapy scheme respect demographic, clinical and cost variables in pediatric patients whit complicated apendicitis. MATERIALS AND METHODS. Cross-sectional
analytical study. Population of 133 patients and sample of 93, with complicated appendicitis; 58 received ampicillin + metronidazole + gentamicin and 35 ceftriaxone + metronidazole. The following variables were compared; hospital stay, complications and monetary cost of each scheme. It was performed in the Pediatric Surgery Unit of the Hospital of Specialties Carlos Andrade Marin, during january 2017, through october 2018. The data were analyzed with R-Studio 1.8.366 for Windows. RESULTS. There was no statistical difference regarding hospital stay (p=0.261); complications such as surgical site infection (p=0.196), re-surgical intervention (p=0.653); nor cost (p=0.059). CONCLUSION. Triple vs. Double antibiotic therapy scheme used in complicated appendicitis in pediatrics was compared. No statistically significant differences were found in this preliminary report, how ever with the double scheme the frequency of administration
was lower and exposure to side effects of aminoglycosides was avoided.

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