Periodicidad semestral: flujo continuo.
ISSN - Electrónico: 2661-6947 / DOI: 10.36015 • LILACS BIREME (19784); LATINDEX (20666)
Introduction: Small cell carcinoma of the bladder is a rare neoplasm, which can coexist many times with an urothelial carcinoma. It occurs mainly in males in the seventh and eighth decades of life. Macroscopically it is observed as a solid and polypoid mass and microscopically it is conformed by atypical cells with hyperchromatic nuclei and a high mitotic rate. Case: A 56-year-old man, smoker who has hematuria for six months, and dysuria and difficulty to urinate. In a cystocopy a bladder tumor is identified and a radical cistoprostectomy is performed. Discusion: Small cell vesical carcinoma is uncommon and may coexist with urothelial carcinoma. The anatomical pathological study is fundamental to determine the diagnosis, requiring immunohistochemical markers such as synaptophysin, CD56, chromogranin and enolase. Surgery, chemotherapy and radiation are used to provide a multidisciplinary treatment of the disease.
Ismaili N. A rare bladder cancer - small cell carcinoma: review and update. Orphanet J Rare Dis [Internet]. 2011 [citado 5 Mar 2017]. 6:75. Disponible en: http://www.ojrd.com/content/6/1/75
Rodríguez F, Trinidad S, Uribe N, Sotomayor M. Carcinoma de células pequeñas primario de vejiga tratado mediante cistectomía parcial. Presentación de un caso. Actas Urol Esp [Internet]. 2005 [citado 27 Mar 2017]; 29 (9):899-901. Disponible en: http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0210-48062005000900013
Stenzl A, Cowan N, De Santis M, Kuczyk M, Merseburger A, Ribal M. Guía clínica sobre el cáncer de vejiga con invasión muscular y metastásico. European Association of Urology [Internet]. 2010 [citado 15 May 2017]. p. 275. Disponible en: http://www.aeu.es/UserFiles/03-Guía Clínica sobre Cáncer de Vejiga con Invasión.Pdf
Ghervan L Zaharie A, Ene B, Elec FI. Small-cell carcinoma of the urinary bladder: where do we stand? Clujul Med [Internet]. 2017 [citado 15 Abr 2017]. 90 (1): 13-17. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/28246491
Guerra N. Revisión sobre carcinoma vesical de células pequeñas. Salud (ciencia) [Internet]. 2006. [citado 16 Abr 2017] 15(1): 450-451. Disponible en: https://www.siicsalud.com/dato/sic/151/expertos151.pdf
Church DN, Bahl A. Clinical review – Small cell carcinoma of the bladder. Cancer Treatment Reviews
[Internet]. 2006 [citado 15 Abr 2017] 32, 588– 593. Disponible en: http://bibliomed.bib.uniud.it/utenti/2212/review06.pdf
Aragón AR, Pineda ME. Puente FE. Zavala A. Carcinoma neuroendócrino vesical. Revista Cir Cir [Internet]. 2014[citado 2 May 2017]. 82(3) 3. Disponible en: http://www.medigraphic.com/pdfs/circir/cc-2014/cc143o.pdf
Pant M, Lopez A, Montironi R, MacLennan GT, Cheng L. Small cell carcinoma of the urinary bladder. Histol Histopathol [Internet] .2010 [citado 12 May 2017]. 25: 217-221. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/20017108
Comarmond C, Cacoub P. Granulomatosis with polyangiitis (Wegener): clinical aspects and reatment. Autoimmun Rev. 2014 Nov; 13(11):1121- 5
Ulamec M, Krušlin B. Neuroendocrine tumors in the urinary bladder: a literature review. Endocrine Oncology and Metabolism [Internet] .2016 [citado 12 May 2017]. p. 43-46. Disponible en: http://eom.hdeo.eu/wp-content/uploads/2016/04/5Ulamec.pdf
Geynisman DM, Handorf E, Wong YN, Doyle J, Plimack ER, Horwitz EM. Advanced small cell carcinoma of the bladder: clinical characteristics, treatment patterns and outcomes in 960 patients and comparison with urothelial carcinoma. Cancer Medicine [Internet]. 2015 [citado 12 May 2017] . p. 192-199. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/26679712
Gkirlemis K, Miliadou A, Koukourakis G, Sotiropoulou A. Small cell carcinoma of the bladder: A search of the current Literatura. J BUON [Internet] 2013 [citado 12 May 2017]; 18(1):220-226. Disponible en: http://www.jbuon.com/pdfs/220-226-Gkirlemis-Small%20cell.pdf
Qarro A, Ammani A, Bazine K; Najoui M, Samir J, Alami M. Synchronous primary malignancies of the male urogenital tract. Can Urol Assoc J [Internet] 2014 [citado 12 May 2017] 8(5-6):e353-5. Disponible en: http://dx.doi.org/10.5489/cuaj.1532
Ka-Siong V, Chan P. Primary Small Cell Carcinoma of the Upper Urinary Tract. J Chin Med Assoc [Internet]. 2010 [citado 12 May 2017]. 73(3): 173-176. Disponible en: http://homepage.vghtpe.gov.tw/~jcma/73/3/173.pdf
Akamatsu H, Nomiya T, Harada M, Oota I, Ichikawa M, Miwa M. Bladder-Sparing Approach with Radiotherapy in Patients with Small Cell Carcinoma of the Bladder. Journal of Cancer Therapy [Internet], 2014 [citado 112 May 2017], 5, 797-805. Disponible en:https://www.scirp.org/journal/PaperInformation aspx?PaperID=47881
The authors who publish in this journal accept the following conditions:
1. The authors retain the copyright and grant to the CAMbios MEDICAL-SCIENTIFIC JOURNAL HECAM the right of the first publication, with the work registered with the Creative Commons attribution license, which allows third parties to use the published material provided that they mention the authorship of the work and the first publication in this journal.
2. Authors can make other independent and additional contractual agreements for the non-exclusive distribution of the version of the article published in this journal (for example, include it in an institutional repository or publish it in a book) as long as it clearly indicates that the work was published. for the first time in the CAMbios MEDICAL-SCIENTIFIC JOURNAL HECAM.